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Wiley is using this site to highlight newly published content – all free of access - related to the current COVID-19 outbreak. The most recent articles can be found below. From the navigation menu above, you will find links to archived content from the past few months, as well as Special Collections compiled by several individual journals and organizations. In addition to this site, Wiley is also making a collection of journal articles and our book chapters on coronavirus research freely available to the global scientific community.
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Novel Coronavirus Outbreak
Most recent articles (newest articles listed first)
Functional Features and Current Applications of the RNA‐Targeting Type VI CRISPR‐Cas Systems
Abstract
Class 2 type VI CRISPR‐Cas systems are characterized by Cas13 effector proteins that exclusively cleave single‐stranded RNA. This review article summarizes current knowledge on structural and mechanistic properties of type VI CRISPR‐Cas systems, gives an overview on reported applications of Cas13‐based tools, and discusses functional features that need further investigation in order to improve their performance.
Intrahospital COVID‐19 infection outbreak management: Keep calm and carry on
Cautions on the laboratory indicators of COVID‐19 patients on and during admission
Abstract
Outline of analyses of the COVID‐19 patients laboratory indicators.
The role and significance of angiotensin‐converting enzyme 2 peptides in the treatment of coronavirus disease 2019
Abstract
The binding of ACE2 to SARS‐CoV‐2‐RBD involved two core regions (31st and 353rd lysine) and 20 amino acids of the ACE2 protein. The mutation of these amino acids could lead to a great change of the binding ability of ACE2 and SARS‐CoV‐2‐RBD, so the efficient ACE2 peptides may effectively block the 2019‐nCoV infection.
Modeling population‐wide testing of SARS‐CoV‐2 for containing COVID‐19 pandemic in Okinawa, Japan
Abstract
Population‐wide testing plays a vital role in containing COVID‐19, and possible scenarios for decreasing COVID‐19 incidence by combining population‐wide screening and/or social distancing policy are explored. We reveal that mass testing that mobilizes sufficient target population at an adequate frequency will help contain the pandemic, and solely imposing a circuit breaker will not bring a favorable outcome in the long run. Also, mass testing presents implications for minimizing a period of lockdown.
